How our oral health affects our overall wellbeing

How our oral health affects our overall wellbeing

How our oral health could make or break us

Our bodies function as complex, interconnected systems, where each part influences the others. Close attention to how oral health impacts chronic diseases has resulted in increasingly clear research findings. More and more studies now demonstrate the connection between the condition of our mouths and our general health. You may have even seen this link highlighted in the recent Australian Dental Association’s statement on oral and systemic disease. Oral health is now understood to impact the entire body, from your heart and your metabolism, right through to the health of your brain.

Poor oral health could even be considered as increasing one’s risk of an early death. Given it is associated with an increase in one’s likelihood of developing chronic diseases like diabetes and heart disease, it really cannot be neglected. Evidence suggests it’s a two-way street, since poor oral health can exacerbate chronic diseases, while chronic diseases can increase the risk of dental problems. Just like an airplane needs both its wings to soar, we rely on excellent oral and overall health for a long and happy life.

What’s the oral-systemic connection?

There are three ways in which oral health connects to chronic diseases. Direct impacts, indirect impacts, and shared risk factors each reveal different ways the condition of one’s mouth is closely linked to their overall health.

Direct impact

This occurs when chronic illnesses or their treatments directly influence oral health, and vice versa. For instance, diabetes, especially when poorly controlled, can lead to high blood sugar levels, creating an environment that promotes gum inflammation (periodontitis). This is because excess sugar in the blood can feed harmful bacteria in the mouth, increasing the risk of infection and gum disease. On the flip side, untreated gum disease leads to chronic inflammation that can spread throughout the body. This systemic inflammation makes it harder for the body to respond to insulin, exacerbating diabetes and leading to a vicious cycle of worsening oral and overall health.

Indirect impact

Oral health and chronic diseases can also affect one another indirectly through treatments, medications, and lifestyle factors. Many people with chronic conditions take medications, but these can have unintended side effects on oral health. For example, antidepressants, blood pressure medications, and certain cancer treatments can cause dry mouth (xerostomia). When saliva production decreases, there’s less natural protection against harmful bacteria, leading to an increased risk of cavities and gum disease.

Moreover, oral health issues like tooth decay, gum disease, or missing teeth can make it difficult to chew, which may limit someone’s ability to eat a healthy, balanced diet. Poor nutrition can further worsen chronic conditions like diabetes, heart disease, or digestive disorders, creating a negative feedback loop where one problem worsens the other.

Shared risk factors

Many oral health issues and chronic diseases share common lifestyle habits and risk factors that can harm both areas. Smoking is a well-known cause of gum disease and tooth loss, but it’s also a major risk factor for chronic illnesses like heart disease, lung disease, and cancer. Smokers are more likely to have inflamed gums, increased plaque buildup, and a weakened immune response, which makes it harder for the body to fight infections. Quitting smoking can significantly improve both oral health and reduce the risk of chronic diseases.

A diet high in sugar contributes to tooth decay and gum disease, as well as being a key factor in the development of conditions like obesity and type 2 diabetes. Cutting down on sugar can improve your oral health and overall well-being, reducing your chances of developing chronic diseases. Likewise, a nutrient-rich diet that includes plenty of vegetables, fruits, and whole grains can support healthy teeth and gums while reducing the risk of heart disease, diabetes, and other chronic illnesses.

Is your oral microbiome your friend or foe?

Your oral microbiome is the community of microorganisms, including bacteria, fungi, and viruses, that naturally make their home in the various parts of your mouth. Under normal conditions, these microbes coexist harmoniously, playing a role in maintaining oral health by aiding digestion and protecting against harmful pathogens.

However, when the balance of these microbes is disrupted—whether through poor oral hygiene, diet, or other factors—it leads to a state called dysbiosis. This imbalance can result in an overgrowth of harmful bacteria that cause inflammation and infection, such as gum disease (periodontitis), and can weaken the body’s ability to fight off other health threats.

Dysbiosis in the mouth doesn’t just stay localised—it can have far-reaching effects on overall health. Research has increasingly linked oral microbial imbalances to serious chronic diseases, such as diabetes, heart disease, and Alzheimer’s disease.

oral microbiome

Which common chronic diseases are linked to oral health?

Heart disease: Gum disease (periodontal disease) triggers inflammation, allowing harmful bacteria to enter the bloodstream. This can contribute to plaque buildup in the arteries and increase the risk of heart disease. Conversely, heart disease can compromise the immune system, making individuals more susceptible to gum infections.

Diabetes: There is a two-way relationship between diabetes and gum disease. Diabetes weakens the body’s ability to fight infections, which can worsen gum disease. In turn, the chronic inflammation from gum disease makes it harder for the body to regulate blood sugar, complicating diabetes management.

Alzheimer’s disease: Emerging research indicates a potential link between chronic gum infections and Alzheimer’s disease. The inflammatory response caused by gum disease may contribute to cognitive decline, though this connection is still under investigation.

Respiratory illness: Poor oral hygiene allows harmful bacteria from the mouth to be inhaled into the lungs, potentially leading to respiratory infections such as pneumonia, especially in those with weakened immune systems.

Mental health: Chronic dental pain and discomfort can significantly impact mental health, contributing to conditions like anxiety and depression. Additionally, concerns about bad breath, tooth appearance, or other oral health issues can negatively affect self-esteem and social interactions.

Obesity: Obesity is associated with increased systemic inflammation, which can exacerbate gum disease. Additionally, poor dietary habits linked to obesity, such as high sugar consumption, contribute to oral health issues like tooth decay and gum inflammation.

Cancer: There is evidence to suggest a link between poor oral health and certain types of cancer, particularly oral cancers like squamous cell carcinoma. Risk factors such as smoking, alcohol consumption, and chronic gum inflammation play significant roles in this connection.

diabetes

What’s the mechanism of the impact?

Hormone production: Inflammation in the mouth can interfere with the production of essential hormones, including enzymes like salivary amylase, which aid in digestion. This disruption may impair the body’s ability to properly break down food and absorb nutrients, impacting overall health.

Metabolic syndrome: Chronic inflammation from gum disease can exacerbate insulin resistance, a key factor in metabolic syndrome. This condition involves a combination of health issues, such as high blood pressure, elevated blood sugar, and abnormal cholesterol levels, increasing the risk of heart disease and diabetes.

Gut microbiome: The oral microbiome plays a crucial role in influencing the balance of bacteria in the gut. Maintaining a healthy oral environment can support gut health, potentially lowering the risk of metabolic conditions like obesity and type 2 diabetes by preventing harmful bacteria from disrupting gut flora.

Immune system: Poor oral health can lead to chronic inflammation, which places ongoing stress on the immune system. This weakened immune response can make the body more vulnerable to infections and systemic health problems beyond the mouth.

Simple steps to impeccable oral health

Maintaining outstanding oral health can significantly improve your overall health and quality of life. It’s worth the effort!

Brush and floss daily: Brush your teeth twice a day for at least two minutes, and floss once daily to remove plaque and bacteria between teeth, preventing gum disease and tooth decay.

Regular dental checkups: Schedule routine dental visits every six months to catch and address issues early, such as cavities, gum disease, or oral infections, before they worsen.

Eat a balanced diet: Focus on a diet rich in fruits, vegetables, lean proteins, and whole grains. Limit sugary foods and drinks, which can fuel the growth of harmful bacteria and lead to cavities and gum problems.

Stay hydrated: Drink plenty of water throughout the day. Water helps wash away food particles and bacteria, while staying hydrated supports saliva production, which is essential for maintaining a healthy oral environment.

Eat a balanced diet

Use fluoride: Incorporate fluoride toothpaste and mouthwash into your oral care routine. Fluoride strengthens tooth enamel, making it more resistant to decay.

Quit smoking: Smoking increases the risk of gum disease, tooth loss, and oral cancers. Quitting smoking is a win-win: it benefits your oral health and your overall physical health.

Chew sugar-free gum: Chewing sugar-free gum after meals can stimulate saliva production. This helps neutralise acids and wash away food particles, protecting your teeth between brushings.

Limit alcohol consumption: Excessive alcohol can dry out the mouth and erode enamel, increasing the risk of gum disease and oral infections. Moderating alcohol intake helps protect both your mouth and body.

Incorporating these habits can help protect your smile and support your overall health.

Your healthy smile makes for a healthier you

Caring for your oral health goes so much further than giving you a beautiful smile—it’s a truly valuable commitment to your overall well-being. It’s an essential part of proper self-care that simply can’t be neglected. Regular brushing, flossing, and dental checkups are simple practices, yet they can protect your teeth, nurture your body, and reduce the risk of chronic diseases. If living a long and fulfilling life is important to you, then a great oral health routine is well worth the effort.

When you prioritise your oral health, you invest in your confidence, vitality, and peace of mind for life. So, keep smiling, cherish each moment, and take pride in your healthy smile which underpins your bright future!

How oral bacteria (F. nucleatum) fuels cancer growth

How oral bacteria (F. nucleatum) fuels cancer growth

How oral bacteria (F. nucleatum) fuels cancer growth

For the longest time, cancer research has focused on on genetic mutations and environmental factors in its search for preventative treatments and cures. But recently, scientists have uncovered a surprising culprit which may increase cancer growth and help it spread: bacteria. One bacterium in particular, Fusobacterium nucleatum (F. nucleatum), which originates in the oral cavity, has been linked to increased risk of cancers in the mouth and far beyond.

What is F. nucleatum?

F. nucleatum is a cigar-shaped bacteria which is a common resident of the mouth, throat and intestine. While typically harmless, this anaerobic bacteria has been found in higher levels in tumours of the colon, breast, head and neck. This finding has researchers wondering: is F. nucleatum just a bystander in cancer, or does it actively contribute to the disease?

Cancers linked to F. nucleatum

Colorectal cancer: Research has consistently shown a strong association between F. nucleatum and colorectal cancer. In fact, a recent study even identified a specific subtype of F. nucleatum known as Animalis, which is particularly linked to more aggressive forms of colorectal tumours.

Oral cancer: F. nucleatum is commonly found in large quantities within biofilms that coat oral squamous cell carcinomas, indicating a potential involvement in the development of oral cancer.

Breast cancer: The acceleration of tumour growth and the spread of cancer cells (metastasis) in breast cancer cases has also been shown to have a connection with an abundance of F. nucleatum.

How oral bacteria (F. nucleatum) fuels cancer growth

How does F. nucleatum promote cancer?

Researchers are still piecing together the exact mechanisms, but several theories suggest how F. nucleatum can contribute to cancer development:

Boosting cell growth: F. nucleatum has the ability to interact with our cells in a way that accelerates their growth and prevents them from undergoing natural cell death processes. This abnormal stimulation of cell growth can contribute to the formation of tumours.

Breast cancer: The acceleration of tumour growth and the spread of cancer cells (metastasis) in breast cancer cases has also been shown to have a connection with an abundance of F. nucleatum.

Causing inflammation: When F. nucleatum is present, it triggers our body to release substances that lead to inflammation. Chronic inflammation is a known factor in cancer development, as it creates an environment that supports the growth and spread of cancerous cells.

Dodging the immune system: The bacterium has the clever ability to deceive our immune system, impairing its effectiveness in recognising and eliminating cancer cells. By evading the immune response, Fusobacterium nucleatum provides an advantage to cancer cells, allowing them to thrive and proliferate.

Assisting in tumour spread: F. nucleatum plays a role in facilitating the spread of cancer cells by aiding in their invasion of nearby tissues. It achieves this by breaking down barriers between cells and promoting the movement of cancer cells to other parts of the body. This capability enhances the aggressiveness and metastatic potential of cancer.

These are just some of the ways F. nucleatum might be working behind the scenes in cancer development. Research is still ongoing, but the link between this bacterium and cancer is becoming increasingly clear.

How oral bacteria (F. nucleatum) fuels cancer growth

Is everyone with F. nucleatum at risk of cancer?

Having F. nucleatum doesn’t guarantee you’ll get cancer. Many factors contribute to cancer development, and F. nucleatum might be one piece of the puzzle. Additionally, the exact mechanisms at play are still being explored in ongoing research.

Right now, F. nucleatum isn’t used for routine cancer screening. However, understanding this connection might lead to new diagnostic tools to identify cancers harbouring this bacterium. Additionally, researchers are exploring the possibility of targeting F. nucleatum with antibiotics or developing vaccines to prevent its colonisation in tumours.

What can you do?

While there’s no single action to eliminate cancer risk from F. nucleatum, here are some general steps that can promote good health:

Oral hygiene routine: Maintaining excellent oral hygiene practices like diligent brushing and flossing can help reduce the overall burden of bad bacteria in the mouth.

Regular dental care: Visit your dentist for regular checkups and cleanings to prevent gum disease, a breeding ground for F. nucleatum. Early detection and treatment can make a big difference.

Oral pathogen tests: A few dental clinics now offer advanced oral pathogen screanning and tests to identify specific bacteria in your mouth. These tests can provide more targeted information about your oral health and may help your dentist develop a more personalised treatment plan.

Prioritise preventive care: Regular checkups with your doctor allow for early detection of various cancers, leading to better treatment outcomes.

Embrace a healthy lifestyle: A balanced diet rich in fruits, vegetables, and whole grains, combined with regular exercise and maintaining a healthy weight, can significantly reduce your overall cancer risk.

Consider probiotics: Probiotics may help create a more balanced gut microbiome, potentially reducing the growth of harmful bacteria like F. nucleatum.

How oral bacteria (F. nucleatum) fuels cancer growth

Healthy habits, healthy you

In light of ongoing research on the connection between F. nucleatum and cancer, the significance of a holistic approach to overall health is clearer than ever. Prioritising good oral hygiene, regular check-ups, a balanced diet and a healthy lifestyle helps us build a strong foundation to fight off potential health problems. After all, a healthy body is naturally better at defending itself against health challenges. So, make great oral care habits part of your lifestyle—it’ll help you become a stronger, more resilient version of yourself!

Consider talking to your dentist or doctor about your specific risk factors and how to maintain optimal health.